Trans-1,2-Dichloroethylene is an industrial solvent that can enter water from factory discharges. It may damage the liver and nervous system if consumed.

Trans-1,2-Dichloroethylene is a synthetic chemical primarily used as an industrial solvent and in the production of other chemicals. It can enter drinking water through improper disposal or leaks from manufacturing facilities. This compound is typically measured in parts per billion (ppb) using gas chromatography. While less common than its cis isomer, trans-1,2-Dichloroethylene is more stable and persistent in the environment. The EPA has set a maximum contaminant level of 100 ppb for this substance in drinking water to protect public health.